AWARENESS TIMES
Sierra Leone News & Information

State House | Press Union | Lumley Beach | AllAfrica | SL-Web

www.awarenesstimes.com

  Giving Knowledge to the People
welcome to sierra leone's premier news source
Last Updated: Apr 11th, 2017 - 17:16:21 
Front Page 
 
 NEWS
 Breaking News
 Local News
 Politics
 Photo News
 Video News
 
 EDITORIALS
 
 FROM OUR TEAM
 
 COMMENTS & OPINIONS
 Moiie's Column
 
 SPECIAL REPORTS
 Afsatu Kabba
 
 FEATURES
 
 ENTERTAINMENT
 
 PROFILES
 Role Models
 Awareness Lady
 Common Man
 
 THE ECONOMY
 
 NOTICES & DOCUMENTS
 Special Messages
 Legal Matters
 Obituaries
 
 PAID SUPPLEMENTS
 
 ADVERTISEMENTS
 
 SATIRE
Search


Published online by
Sylvia Blyden Dot Com

17 Garrison Street,
Freetown,
Sierra Leone.
Tel: +232-77-772001
Tel: +232-88-321000
Tel: +232-76-350077
Tel: +232-30-321001
Email:
editor@news.sl
Website:
www.awarenesstimes.com

NEWS  

Trial to evaluate three Ebola vaccination strategies launched in West Africa
By
Apr 11, 2017, 17:00
Email this article
 Printer friendly page

Thursday, 06 April 2017

 

A large clinical trial of candidate Ebola vaccines has been launched in West Africa by the PREVAC international research consortium, which includes the London School of Hygiene & Tropical Medicine.

 

The study aims to identify vaccination strategies with the most promise to protect people from contracting the Ebola virus in order to prevent or quickly control a future outbreak.

 

There is currently no approved vaccine to prevent Ebola, although some are at late stages of development. Pursuing research on vaccination strategies to prevent the disease is essential, as several questions remain regarding the durability of the immune response of candidate vaccines. The PREVAC trial will evaluate the speed, intensity and duration of the immune responses generated by the various vaccination strategies, as well as the safety and tolerability of the various vaccines, particularly in children. 


The PREVAC (Partnership for Research on Ebola VACcination) consortium brings together the health authorities of three countries in West Africa — Guinea, Liberia and Sierra Leone—and their international partners, the National Institute of Health and Medical Research (Inserm) in France, the National Institute of Allergy and Infectious Diseases of the National Institutes of Health (NIAID/NIH) in the United States, and the London School of Hygiene & Tropical Medicine.

 

The pharmaceutical companies Janssen Vaccines & Prevention B.V., part of the Janssen Pharmaceutical Companies of Johnson & Johnson, Bavarian Nordic and Merck Sharp &Dohme, Corp (MSD outside USA and Canada), are supplying the experimental vaccines being tested.


The PREVAC trial is a Phase 2, randomised trial that aims to compare three experimental Ebola vaccination strategies with placebos, in order to determine whether they are safe and able to trigger a durable immune response that can protect against Ebola. 

 

More than 5,000 adults and children living in countries at the epicentre of the 2014-16 West Africa Ebola epidemic will be enrolled. The study will initially be conducted at two sites in Guinea and one site in Liberia, with an additional site in Sierra Leone awaiting confirmation.

 

In its first stage, the trial will evaluate one of the three strategies, a prime-boost vaccination combining two different vaccines (Ad26.ZEBOV made by Janssen and MVA-BN-Filo made by Bavarian Nordic) compared with a similar placebo regimen. Enrolment into this stage in Guinea and Liberia began on 27th March and 3rd April 2017, respectively. In a second stage, which is expected to start in the second half of 2017, the trial will evaluate all three vaccination strategies, including two additional strategies involving Merck’s rVSV”G-ZEBOV-GP vaccine.

 

Yves Levy, Inserm Chairman and CEO; Anthony S. Fauci, Director of the National Institute of Allergy and Infectious Diseases at NIH; and Peter Piot, Director of the London School of Hygiene & Tropical Medicine, said: “We, Inserm, NIH, and LSHTM, have designed and launched this unique international research partnership with our colleagues from the West African countries most affected by Ebola virus disease to answer remaining questions regarding the safety and immunogenicity of candidate Ebola vaccine strategies and thereby enable us to better fight future Ebola outbreaks.”  


© Copyright by Awareness Times Newspaper in Freetown, Sierra Leone.

Top of Page

Latest Headlines
NEWS
Sierra Leone News : Chinese Ambassador Assures Commitmentto Koroma’s Priorities
Sierra Leone News : VP Foh Launches ACTB Savings and Loans Accounts
Sierra Leone News : Charliesco Donates 85 bags of rice & Money to 58 Mosques
EDITORIALS
Sierra Leone: Why Always Port Loko? Why? Why?
$200,000 AFCOM Scandal: Why VP Foh Must Be Very Careful
Front Page Editorial Advise... Tiffy Tiffy AFCOM's $200,000 Fake VSAT Contract & Hon VP Foh
FROM OUR TEAM
Sierra Leone: Unwrapping Yasmin Jusu Sheriff
COMMENTS & OPINIONS
Madam Zainab Sheriff Bangura For Lunsar Constituency
Sierra Leoneans still shamefully abusing social media to mislead public and tarnish the names of Government and country
7-storey APC/ CPC building and the hue and cry by detractors: The points being missed by the rabble-rousers
SPECIAL REPORTS
Sierra Leone Cabinet Minister Calls On Police to Investigate Conspiracy to Defraud Donor Funds
FEATURES
The Renaissance of Sierra Leone through the lenses of Attitudinal and Behavioural Change
Towards a modernised education system which can meet the challenges and opportunities of our future
Sierra Leone Social Welfare Deputy Calls Up Bizarre Press Conference
ENTERTAINMENT
No articles available.
PROFILES
OJU Wilson - Your contribution to the Human Rights Struggle and the Rule of Law will never be forgotten
Sierra Leone Politics : Alhaji Osman Foday Yansaneh, a Muslim Steering an all-inclusive APC Secretariat
TRIBUTE TO DR. V R WILLOUGHBY
THE ECONOMY
No articles available.
NOTICES & DOCUMENTS
President Koroma Leaves for Germany
Standard Chartered Regional Head of Compliance, Africa & Middle East Visits Sierra Leone
First Lady Sia Nyama Koroma Visits Sierra Leonean Patients At Apollo Hospital In New Delhi, India
PAID SUPPLEMENTS
No articles available.
ADVERTISEMENTS
No articles available.
SATIRE
SATIRE: Question: What is this rabbit laughing hysterically about???
RETRACTION!!

Copyright © 2005 - 2010, Awareness Times Sierra Leone; All Rights Reserved.
Hosted & Designed by West Africa Dot Net